3.8 Article

Complete Genome Sequences of Eight Helicobacter pylori Strains with Different Virulence Factor Genotypes and Methylation Profiles, Isolated from Patients with Diverse Gastrointestinal Diseases on Okinawa Island, Japan, Determined Using PacBio Single-Molecule Real-Time Technology

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GENOME ANNOUNCEMENTS
卷 2, 期 2, 页码 -

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AMER SOC MICROBIOLOGY
DOI: 10.1128/genomeA.00286-14

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  1. Okinawa Prefectural Government
  2. Grants-in-Aid for Scientific Research [25860545, 24406015, 26640114, 25293104, 24659200] Funding Source: KAKEN

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We report the complete genome sequences of eight Helicobacter pylori strains isolated from patients with gastrointestinal diseases in Okinawa, Japan. Whole-genome sequencing and DNA methylation detection were performed using the PacBio platform. De novo assembly determined a single, complete contig for each strain. Furthermore, methylation analysis identified virulence factor genotype-dependent motifs.

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