期刊
TECHNOLOGY
卷 2, 期 1, 页码 13-22出版社
WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.1142/S2339547814300029
关键词
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资金
- National Institutes of Health [R00DK080942, R01DK096075, R01EB008678]
- Shriners Hospitals for Children
Organ culture systems are instrumental as experimental whole-organ models of physiology and disease, as well as preservation modalities facilitating organ replacement therapies such as transplantation. Nevertheless, a coordinated system of machine perfusion components and integrated regulatory control has yet to be fully developed to achieve long-term maintenance of organ function ex vivo. Here we outline current strategies for organ culture, or organomatics, and how these systems can be regulated by means of computational algorithms, or organometrics, to achieve the organ culture platforms anticipated in modern-day biomedicine.
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