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J. Yu et al.
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Yun Liu et al.
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J. D. Herman et al.
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Neil K. Singla et al.
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Jiri Nossent et al.
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Sensitivity analysis approaches applied to systems biology models
Z. Zi
IET SYSTEMS BIOLOGY (2011)
A workflow for global sensitivity analysis of PBPK models
Kevin McNally et al.
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SensSB: a software toolbox for the development and sensitivity analysis of systems biology models
Maria Rodriguez-Fernandez et al.
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Andrea Saltelli et al.
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CY Wu et al.
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S Joe et al.
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