期刊
JOURNAL OF ORGANOMETALLIC CHEMISTRY
卷 869, 期 -, 页码 1-10出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jorganchem.2018.05.014
关键词
Ferrocene; 5-Arylidene-thiazolidinone; Knoevenagel condensation; Electrochemistry; Antimicrobial activity; Antioxidant activity
资金
- Ministry of Education, Science and Technological development of the Republic of Serbia [172034]
Synthesis of twenty novel 5-arylidene-2-ferrocenyl-1,3-thiazolidin-4-ones has been achieved in good to excellent yields by the Knoevenagel condensation of 2-ferrocenyl-1,3-thiazolidin-4-ones with aromatic aldehydes. The reaction was performed by refluxing the mixture of reactants and potassium tert-butoxide in dioxane overnight. All new compounds were characterized by the IR and NMR spectral data, and their electrochemical properties were investigated using the cyclic voltammetry. The X-ray crystal structure of one of the representative thiazolidin-4(1H)-ones is also presented. All obtained products were evaluated for their in vitro antioxidant, antibacterial and antifungal activity. (C) 2018 Elsevier B.V. All rights reserved.
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