期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 83, 期 7, 页码 4250-4256出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.8b00279
关键词
-
资金
- National Natural Science Foundation of China [21202009, 21672217]
Asymmetric fluorination of alpha-branched aldehydes catalyzed by chiral primary amines under mild conditions has been developed. Both enantiomers could be obtained with good yields (up to 96%) and a high enantioselectivity (up to 90% ee) by a simple swap of the fluorination reagents.
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