期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 83, 期 6, 页码 3354-3360出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b03055
关键词
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资金
- National Natural Science Foundation of China [21572203, 21472140]
- Zhejiang Provincial Natural Science Foundation [LZ16B020001]
We report an efficient palladium-catalyzed approach to the synthesis of benzoxazole derivatives via sequential heteroarylation/acylation reaction of iodobenzenes. Three readily available starting materials, iodobenzenes, anhydrides, and benzoxazoles, were smoothly coupled to form new C-C bonds at the ortho and ipso positions of the iodobenzenes to afford 2-heteroaryl-3-acylbenzene derivatives in good yields.
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