期刊
CHILD DEVELOPMENT
卷 85, 期 2, 页码 501-512出版社
WILEY
DOI: 10.1111/cdev.12136
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资金
- NCATS NIH HHS [UL1 TR000427] Funding Source: Medline
- NCRR NIH HHS [RR000167, P51 RR000167, UL1 RR025011, 1UL1RR025011] Funding Source: Medline
- NICHD NIH HHS [P30 HD003352] Funding Source: Medline
- NIH HHS [P51 OD011106] Funding Source: Medline
- NIMH NIH HHS [R01 MH061285, T32 MH018931, MH61285] Funding Source: Medline
Child maltreatment often has a negative impact on the development of social behavior and health. The biobehavioral mechanisms through which these adverse outcomes emerge, however, are not clear. To better understand the ways in which early life adversity affects subsequent social behavior, changes in the neuropeptide oxytocin (OT) in children (n=73) aged 8.1-11.5years following a laboratory stressor were examined. Girls with histories of physical abuse have higher levels of urinary OT and lower levels of salivary cortisol following the stressor when compared to controls. Abused and control boys, however, do not differ in their hormonal responses. These data suggest that early adversity may disrupt the development of the stress regulation system in girls by middle childhood.
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