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Regulation of Autophagy by Glucose in Mammalian Cells
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Cells (2012)
Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation
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AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2011)
Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytes
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AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2011)
Systems biology of the autophagy-lysosomal pathway
Anil G. Jegga et al.
AUTOPHAGY (2011)
Diabetes as a risk factor for Alzheimer's disease: insulin signalling impairment in the brain as an alternative model of Alzheimer's disease
Christian Hoelscher
BIOCHEMICAL SOCIETY TRANSACTIONS (2011)
A deadly spread: cellular mechanisms of α-synuclein transfer
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CELL DEATH AND DIFFERENTIATION (2011)
4-Hydroxynonenal Inhibits SIRT3 via Thiol-Specific Modification
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CHEMICAL RESEARCH IN TOXICOLOGY (2011)
Rotenone, Paraquat, and Parkinson's Disease
Caroline M. Tanner et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2011)
Assessing bioenergetic function in response to oxidative stress by metabolic profiling
Brian P. Dranka et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
α-Synuclein overexpression impairs mitochondrial function by associating with adenylate translocator
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INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
Complex Inhibitory Effects of Nitric Oxide on Autophagy
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MOLECULAR CELL (2011)
Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
Laura A. Volpicelli-Daley et al.
NEURON (2011)
The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming
C. H. Eng et al.
ONCOGENE (2011)
TFEB Links Autophagy to Lysosomal Biogenesis
Carmine Settembre et al.
SCIENCE (2011)
Nitrate-Nitrite-Nitric Oxide Pathway Implications for Anesthesiology and Intensive Care
Eddie Weitzberg et al.
ANESTHESIOLOGY (2010)
Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia
Jonathan Wills et al.
EXPERIMENTAL NEUROLOGY (2010)
Cellular effects of peptide and protein hydroperoxides
Aldwin Suryo Rahmanto et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
What Part of NO Don't You Understand? Some Answers to the Cardinal Questions in Nitric Oxide Biology
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JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The Transgenic Overexpression of α-Synuclein and Not Its Related Pathology Associates with Complex I Inhibition
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JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
LRRK2 G2019S Mutation Induces Dendrite Degeneration through Mislocalization and Phosphorylation of Tau by Recruiting Autoactivated GSK3β
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JOURNAL OF NEUROSCIENCE (2010)
Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease
Lonnie Schneider et al.
MOLECULAR NEURODEGENERATION (2010)
The use of PET in Alzheimer disease
Agneta Nordberg et al.
NATURE REVIEWS NEUROLOGY (2010)
Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention
Malu G. Tansey et al.
NEUROBIOLOGY OF DISEASE (2010)
Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo
Shankar J. Chinta et al.
NEUROSCIENCE LETTERS (2010)
How mitochondria produce reactive oxygen species
Michael P. Murphy
BIOCHEMICAL JOURNAL (2009)
Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells
Mordhwaj S. Parihar et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
The Neurodegenerative Mitochondriopathies
Russell H. Swerdlow
JOURNAL OF ALZHEIMERS DISEASE (2009)
Increased Enzymatic O-GlcNAcylation of Mitochondrial Proteins Impairs Mitochondrial Function in Cardiac Myocytes Exposed to High Glucose
Yong Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1
Jeff Blackinton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions
Yaping Chu et al.
NEUROBIOLOGY OF DISEASE (2009)
α-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity
Guangwei Liu et al.
NEUROSCIENCE LETTERS (2009)
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
Paula Desplats et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
Kelvin C. Luk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo
Valerie Cullen et al.
MOLECULAR BRAIN (2009)
Metabolic phenotyping in health and disease
Elaine Holmes et al.
CELL (2008)
Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
Latha Devi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
Scott A. Yuzwa et al.
NATURE CHEMICAL BIOLOGY (2008)
Redox proteomic identification of 4-Hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease
Tanea Reed et al.
NEUROBIOLOGY OF DISEASE (2008)
Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells
Shaik Shavali et al.
NEUROSCIENCE LETTERS (2008)
Global expression profiling identifies a novel biosignature for protein aggregation R120GCryAB cardiomyopathy in mice
Namakkal S. Rajasekaran et al.
PHYSIOLOGICAL GENOMICS (2008)
Protection by the NDI1 Gene against Neurodegeneration in a Rotenone Rat Model of Parkinson's Disease
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PLOS ONE (2008)
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
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Molecular Brain (2008)
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
Csaba Szabo et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Complex I binding by a virally encoded RNA regulates mitochondria-induced cell death
Matthew B. Reeves et al.
SCIENCE (2007)
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
Ruth Scherz-Shouval et al.
EMBO JOURNAL (2007)
Kainic acid induces early and transient autophagic stress in mouse hippocampus
John J. Shacka et al.
NEUROSCIENCE LETTERS (2007)
Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons
Mats I. Ekstrand et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Mechanisms of Parkinson's disease linked to pathological α-synuclein:: New targets for drug discovery
Virginia M. -Y. Lee et al.
NEURON (2006)
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase
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NATURE GENETICS (2006)
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
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NATURE (2006)
Loss of autophagy in the central nervous system causes neurodegeneration in mice
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NATURE (2006)
Cathepsin D deficiency is associated with a human neurodegenerative disorder
Robert Steinfeld et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases
J Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis
Eija Siintola et al.
BRAIN (2006)
Nitroxia:: The pathological consequence of dysfunction in the nitric oxide-cytochrome c oxidase signaling pathway
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FREE RADICAL BIOLOGY AND MEDICINE (2005)
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo et al.
SCIENCE (2004)
D-β-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
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JOURNAL OF CLINICAL INVESTIGATION (2003)
Efficient principal component analysis for multivariate 3D voxel-based mapping of brain functional imaging data sets as applied to FDG-PET and normal aging
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HUMAN BRAIN MAPPING (2003)
Mutant and wild-type α-synuclein interact with mitochondrial cytochrome C oxidase
H Elkon et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2002)
Environmental risk factors and Parkinson's disease: A metaanalysis
A Priyadarshi et al.
ENVIRONMENTAL RESEARCH (2001)
Microglial secreted cathepsin B induces neuronal apoptosis
PJ Kingham et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Cortical dysfunction in non-demented Parkinson's disease patients -: A combined 31P-MRS and 18FDG-PET study
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BRAIN (2000)
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
A Abeliovich et al.
NEURON (2000)