相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Glia Open Access Database (GOAD): A comprehensive gene expression encyclopedia of glia cells in health and disease
Inge R. Holtman et al.
GLIA (2015)
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models
Taylor R. Jay et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
Inge R. Holtman et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Targeting miR-155 Restores Abnormal Microglia and Attenuates Disease in SOD1 Mice
Oleg Butovsky et al.
ANNALS OF NEUROLOGY (2015)
MS4A Cluster in Alzheimer's Disease
Jing Ma et al.
MOLECULAR NEUROBIOLOGY (2015)
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
Yonit Lavin et al.
CELL (2014)
Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
David Gosselin et al.
CELL (2014)
Sublime Microglia: Expanding Roles for the Guardians of the CNS
Michael W. Salter et al.
CELL (2014)
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
Peter J. Murray et al.
IMMUNITY (2014)
Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
Jia Xue et al.
IMMUNITY (2014)
Macrophage heterogeneity in tissues: phenotypic diversity and functions
Siamon Gordon et al.
IMMUNOLOGICAL REVIEWS (2014)
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
Ye Zhang et al.
JOURNAL OF NEUROSCIENCE (2014)
Identification of a unique TGF-β dependent molecular and functional signature in microglia
Oleg Butovsky et al.
NATURE NEUROSCIENCE (2014)
Genetic variability in the regulation of gene expression in ten regions of the human brain
Adaikalavan Ramasamy et al.
NATURE NEUROSCIENCE (2014)
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
Katie Lunnon et al.
NATURE NEUROSCIENCE (2014)
Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors
Andrea Crotti et al.
NATURE NEUROSCIENCE (2014)
Histone core modifications regulating nucleosome structure and dynamics
Peter Tessarz et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Microglial priming in neurodegenerative disease
V. Hugh Perry et al.
NATURE REVIEWS NEUROLOGY (2014)
The phenotypic variability of amyotrophic lateral sclerosis
Bart Swinnen et al.
NATURE REVIEWS NEUROLOGY (2014)
Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia
Elise Cuyvers et al.
NEUROBIOLOGY OF AGING (2014)
Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction
Marie Orre et al.
NEUROBIOLOGY OF AGING (2014)
Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice
Marie Orre et al.
NEUROBIOLOGY OF AGING (2014)
Priming of microglia in a DNA-repair deficient model of accelerated aging
Divya D. A. Raj et al.
NEUROBIOLOGY OF AGING (2014)
Microglial CR3 Activation Triggers Long-Term Synaptic Depression in the Hippocampus via NADPH Oxidase
Jingfei Zhang et al.
NEURON (2014)
Tau Overexpression Impacts a Neuroinflammation Gene Expression Network Perturbed in Alzheimer's Disease
Paul D. Wes et al.
PLOS ONE (2014)
Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes
Towfique Raj et al.
SCIENCE (2014)
Advances in treating amyotrophic lateral sclerosis: insights from pathophysiological studies
Steve Vucic et al.
TRENDS IN NEUROSCIENCES (2014)
Microglial diversity by responses and responders
Ulla Gertig et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Complement activation in multiple sclerosis plaques: an immunohistochemical analysis
Gillian Ingram et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2014)
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
Christopher N. Parkhurst et al.
CELL (2013)
Latent Enhancers Activated by Stimulation in Differentiated Cells
Renato Ostuni et al.
CELL (2013)
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer's Disease
Bin Zhang et al.
CELL (2013)
Beyond the transcriptome: completion of act one of the Immunological Genome Project
Charles C. Kim et al.
CURRENT OPINION IN IMMUNOLOGY (2013)
Unique transcriptome signature of mouse microglia
Clara Beutner et al.
GLIA (2013)
Microglial Phenotype and Adaptation
B. J. L. Eggen et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2013)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2013)
The microglial sensome revealed by direct RNA sequencing
Suzanne E. Hickman et al.
NATURE NEUROSCIENCE (2013)
High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states
Ronnie Blecher-Gonen et al.
NATURE PROTOCOLS (2013)
Assessment of TREM2 rs75932628 association with Alzheimer's disease in a population-based sample: the Cache County Study
Josue D. Gonzalez Murcia et al.
NEUROBIOLOGY OF AGING (2013)
Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease
Margarita Giraldo et al.
NEUROBIOLOGY OF AGING (2013)
Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation
Wenxin Ma et al.
NEUROBIOLOGY OF AGING (2013)
Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer's disease mouse model
Kerstin T. S. Wirz et al.
NEUROBIOLOGY OF AGING (2013)
TREM2 is associated with the risk of Alzheimer's disease in Spanish population
Bruno A. Benitez et al.
NEUROBIOLOGY OF AGING (2013)
Alzheimer's Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
Ana Griciuc et al.
NEURON (2013)
GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer's Disease
Carlos Cruchaga et al.
NEURON (2013)
Review: Activation patterns of microglia and their identification in the human brain
D. Boche et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2013)
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Thorlakur Jonsson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Immunological Genome Project and systems immunology
Tal Shay et al.
TRENDS IN IMMUNOLOGY (2013)
Microglia: actively surveying and shaping neuronal circuit structure and function
Hiroaki Wake et al.
TRENDS IN NEUROSCIENCES (2013)
A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
Isaac M. Chiu et al.
CELL REPORTS (2013)
Genes and pathways underlying regional and cell type changes in Alzheimer's disease
Jeremy A. Miller et al.
GENOME MEDICINE (2013)
Meta-analysis of gene expression profiling in amyotrophic lateral sclerosis: A comparison between transgenic mouse models and human patients
Christiaan G. J. Saris et al.
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION (2013)
Genome-Wide Association Study of Late-Onset Alzheimer Disease Identifies Disease-Associated Variants in MS4A4/MS4A6E, CD2AP, CD33, and EPHA1
Adam Naj et al.
Alzheimers & Dementia (2012)
Complement receptor 1 (CR1) and Alzheimer's disease
Helen Crehan et al.
IMMUNOBIOLOGY (2012)
Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
David H. Cribbs et al.
JOURNAL OF NEUROINFLAMMATION (2012)
A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals
Manuel Garber et al.
MOLECULAR CELL (2012)
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
Emmanuel L. Gautier et al.
NATURE IMMUNOLOGY (2012)
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
Dorothy P. Schafer et al.
NEURON (2012)
Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
Jacob A. Tennessen et al.
SCIENCE (2012)
Roles of ATP-Binding Cassette Transporter A7 in Cholesterol Homeostasis and Host Defense System
Nobukiyo Tanaka et al.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2011)
Expression Profiling of the Ephrin (EFN) and Eph Receptor (EPH) Family of Genes in Atherosclerosis-related Human Cells
A. Sakamoto et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2011)
Clusterin induces matrix metalloproteinase-9 expression via ERK1/2 and PI3K/Akt/NF-κB pathways in monocytes/macrophages
Young-Jun Shim et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2011)
Spatio-temporal transcriptome of the human brain
Hyo Jung Kang et al.
NATURE (2011)
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
Paul Hollingworth et al.
NATURE GENETICS (2011)
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
Rosa C. Paolicelli et al.
SCIENCE (2011)
Selective Transcription in Response to an Inflammatory Stimulus
Stephen T. Smale
CELL (2010)
Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages
Serena Ghisletti et al.
IMMUNITY (2010)
Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease
Sudha Seshadri et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)
Activation of EphA receptors on CD4+CD45RO+ memory cells stimulates migration
H. L. Holen et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2010)
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Sven Heinz et al.
MOLECULAR CELL (2010)
Regulation of synaptic connectivity by glia
Cagla Eroglu et al.
NATURE (2010)
Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways
Jeremy A. Miller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Histone H3K27ac separates active from poised enhancers and predicts developmental state
Menno P. Creyghton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Florent Ginhoux et al.
SCIENCE (2010)
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2009)
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
Denise Harold et al.
NATURE GENETICS (2009)
The aging brain
Bruce A. Yankner et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)
WGCNA: an R package for weighted correlation network analysis
Peter Langfelder et al.
BMC BIOINFORMATICS (2008)
A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging
Jeremy A. Miller et al.
JOURNAL OF NEUROSCIENCE (2008)
A transcriptome database for astrocytes, neurons, and oligodendrocytes: A new resource for understanding brain development and function
John D. Cahoy et al.
JOURNAL OF NEUROSCIENCE (2008)
Animal models of Alzheimer's disease and frontotemporal dementia
Jurgen Gotz et al.
NATURE REVIEWS NEUROSCIENCE (2008)
Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set
Winnie S. Liang et al.
PHYSIOLOGICAL GENOMICS (2008)
Gene expression changes in the course of normal brain aging are sexually dimorphic
Nicole C. Berchtold et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases
Monika Ray et al.
GENOME BIOLOGY (2008)
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
Bahareh Ajami et al.
NATURE NEUROSCIENCE (2007)
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
Uwe-Karsten Hanisch et al.
NATURE NEUROSCIENCE (2007)
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
Tarjei S. Mikkelsen et al.
NATURE (2007)
Genome-wide mapping of in vivo protein-DNA interactions
David S. Johnson et al.
SCIENCE (2007)
High-resolution profiling of histone methylations in the human genome
Artern Barski et al.
CELL (2007)
TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis
Kazuya Takahashi et al.
PLOS MEDICINE (2007)
Molecular and cellular immune mediators of neuroprotection
Nicolas P. Turrin et al.
MOLECULAR NEUROBIOLOGY (2006)
Aging of the brain, entropy, and Alzheimer disease
David A. Drachman
NEUROLOGY (2006)
Gene expression correlates of neurofibrillary tangles in Alzheimer's disease
Travis Dunckley et al.
NEUROBIOLOGY OF AGING (2006)
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
A Nimmerjahn et al.
SCIENCE (2005)
PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis
A Dakic et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Neuroinflammation in the pathogenesis of amyotrophic lateral sclerosis
P Weydt et al.
NEUROREPORT (2005)
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
AJ Muller et al.
NATURE MEDICINE (2005)
Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
K Takahashi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
EM Blalock et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The chemokine system in diverse forms of macrophage activation and polarization
A Mantovani et al.
TRENDS IN IMMUNOLOGY (2004)
Gene regulation and DNA damage in the ageing human brain
T Lu et al.
NATURE (2004)
Expression of CD33-related siglecs on human mononuclear phagocytes, monocyte-derived dendritic cells and plasmacytoid dendritic cells
K Lock et al.
IMMUNOBIOLOGY (2004)
Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia
G Sessa et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Microarray analysis in Alzheimer's disease and normal aging
R Ricciarelli et al.
IUBMB LIFE (2004)
Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: Transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling
V Colangelo et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
A gene expression profile of Alzheimer's disease
JF Loring et al.
DNA AND CELL BIOLOGY (2001)
分享论文
