期刊
GERIATRICS & GERONTOLOGY INTERNATIONAL
卷 16, 期 5, 页码 577-585出版社
WILEY
DOI: 10.1111/ggi.12514
关键词
mortality; muscle strength; older adults; physical performance; sarcopenia
资金
- Korean Health Technology R&D Project, Ministry for Health, Welfare, and Family Affairs, Republic of Korea [A092077]
- Bio & Medical Technology Development Program of the National Research Fund (NRF) - Korean Governement [2011-0030135]
- National Research Foundation of Korea [2011-0030135] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Aim: The most appropriate muscle index for the definition of sarcopenia has not been agreed on. We aimed to investigate the associations of muscle mass and strength with 5-year mortality and low physical performance. Methods: We included 560 participants aged 65 years or older in the analysis. Muscle and fat mass were assessed by dual-energy X-ray absorptiometry. Leg muscle and grip strength were measured using dynamometers. The clinical outcomes were 5-year mortality and low physical performance (Short Physical Performance Battery score < 9) in 5 years. Associations between muscle indices and clinical outcomes were analyzed. A Cox proportional hazard model for mortality and a logistic regression model for physical performance were used. Results: Decreases in leg muscle and grip strength were significantly associated with 5-year mortality and low physical performance in both sexes. Total muscle mass in men and appendicular skeletal mass in both sexes were associated with mortality, but not with low physical performance. Lower leg muscle strength (OR 0.107; P = 0.020) was an independent predictor of low physical performance in women after adjusting for age, fat, cognition, and depression. Lower leg muscle (OR 0.123; P = 0.031) and lower grip strength (OR 0.950; P = 0.012) were independent predictors of low physical performance in men. Conclusions: Muscle strength is a better indicator of 5-year adverse clinical outcomes of mortality and low physical performance than muscle mass. Muscle strength was an independent predictor of low physical performance in 5 years.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据