A number of quinazolinone derivatives substituted at position-3 are prepared from 3, 1-benzoxazinone. Thus, treatment of 3, 1-benzoxazinon with cyanoacetohydrazide or thionocarbohydrazide gave the quinazolinone derivatives. The quinazolinones have been utilized as synthon for new pyridinone, azete, thiazole, thiazolidinone, thosemicarbazide, and thiosemicarbazone derivatives. The structures of the synthesized compounds were established on the basis of IR, (HNMR)-H-1, mass spectral data, and elemental analyses.
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