期刊
EMERGING INFECTIOUS DISEASES
卷 20, 期 6, 页码 1016-1018出版社
CENTERS DISEASE CONTROL
DOI: 10.3201/eid2006.131627
关键词
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资金
- Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health
We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design.
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