期刊
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
卷 25, 期 3, 页码 206-213出版社
WILEY
DOI: 10.1002/jhbp.529
关键词
Endoscopic retrograde cholangiopancreatography; Interventional radiography; Pancreatic fistula; Postoperative complications
资金
- Korean Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea [HI14C2640]
BackgroundThe use of preoperative biliary drainage (PBD) for managing patients with periampullary cancer awaiting surgery remains controversial. The impact of PBD status and type on surgical outcomes has not been established, leading to a lack of consensus. We aimed to evaluate the impact of PBD on short-term surgical outcomes in curatively resected periampullary cancer. MethodsWe retrospectively reviewed data from patients undergoing curative periampullary cancer resection. A propensity score-matched analysis was performed to adjust for clinical differences. Univariate and multivariate analyses were performed to determine independent risk factors for complications. ResultsThe overall complication rate was significantly higher in patients who underwent PBD (P=0.027). Additionally, complication rates were significantly higher in the endoscopic biliary drainage (EBD) group than in the percutaneous transhepatic biliary drainage (PTBD) group (P<0.001). After propensity score matching, overall complication rates in patients receiving EBD (P<0.001) were significantly higher. PBD type and diagnosis were independent risk factors for complications (hazard ratios: 1.927 for EBD; 1.921 for biliary tract cancer). ConclusionsPreoperative biliary drainage, especially EBD, should not be routinely performed in patients awaiting surgery for periampullary cancer, as it increases the risk of complications.
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