期刊
WORLD JOURNAL OF HEPATOLOGY
卷 6, 期 6, 页码 363-369出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.4254/wjh.v6.i6.363
关键词
Cirrhosis; Portal hypertension; Esophageal varices; Primary prevention; beta-Blockers; Endoscopic band ligation
Variceal bleeding is a life threatening situation with mortality rates of at least 20%. Prophylactic treatment with non-selective beta blockers (NSBBs) is recommended for patients with small varices that have not bled but with increased risk for bleeding. The recommended treatment strategies on primary prevention of variceal bleeding in patients with medium and large-sized varices are NSBBs or endoscopic band ligation. Nitrates, shunt surgery and sclerotherapy are not recommended in this setting. In this review, the most recent data on prevention of esophageal variceal bleeding are presented. Available data derived from randomized-controlled trials suggest both treatment strategies, and according to Baveno V consensus in portal hypertension the choice of treatment should be based on local resources and expertise, patient preference and characteristics, side-effects and contra-indications. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.
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