期刊
JOURNAL OF HAZARDOUS MATERIALS
卷 342, 期 -, 页码 121-130出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jhazmat.2017.07.053
关键词
Gold nanorods; Platinum nanodots; Bimetallic Au@Pt nanorods; Photothermal lysis; Pathogenic bacteria
资金
- National Natural Science Foundation of China [51503087, 21606112]
- China Postdoctoral Fundation Committee [2016M600372]
- Natural Science Foundation of Jiangsu Province [BK20140528, BK20140013, BK20160503]
- Post Doctoral Fund of Jiangsu Province [1601022A]
- Natural Science Fund for Colleges and Universities in Jiangsu Province [17KJB180001]
- Programs of Senior Talent Foundation of Jiangsu University [15JDG137]
Photothermal lysis is an effective method for fast removal of pathogenic bacteria from bacterial contaminated environments and human body, irrespective of bacterial drug resistance. In the present work, a highly effective photothermal agent, Au@Pt nanorods (NRs), was prepared by modification of Pt nanodots with particle size of 5 nm on the surface of Au NRs with a length of ca. 41 nm and a width of ca. 13 nm. The LSPR absorbance band of Au@Pt NRs could be tuned from 755 to 845 nm by changing the Pt loading from 0.05 to 0.2, as compared to Au NRs. The photothermal conversion efficiency of Au@Pt NRs depended on the Pt loading, Au@Pt NRs concentration, and power density. Under NIR irradiation, the Au@Pt-0.1 NRs exhibited the highest efficiency in photothermal lysis of both gram-positive and gram-negative bacteria. The introduction of Pt nanodots on the surface of Au@Pt NRs not only enhanced their photothermal conversions but also enhanced their affinity to bacteria and significantly decreased their cytotoxicity. The photothermal lysis of bacteria over Au@Pt NRs caused the damage onto the cell walls of bacteria, implying that the killing of bacteria probably went through the thermal ablation mechanism. (C) 2017 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据