相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
Xiangpeng Dai et al.
NATURE MEDICINE (2017)
Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation
Pingzhao Zhang et al.
NATURE MEDICINE (2017)
Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors
Hana Janouskova et al.
NATURE MEDICINE (2017)
Cancer Statistics, 2017
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2017)
Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation
Fei Wu et al.
CANCER LETTERS (2017)
Activating transcription factor 2 expression mediates cell proliferation and is associated with poor prognosis in human non-small cell lung carcinoma
Zhenyu You et al.
ONCOLOGY LETTERS (2016)
ATF2 predicts poor prognosis and promotes malignant phenotypes in renal cell carcinoma
Deng-shuang Wu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
Multiple Weak Linear Motifs Enhance Recruitment and Processivity in SPOP-Mediated Substrate Ubiquitination
Wendy K. Pierce et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
The Molecular Taxonomy of Primary Prostate Cancer
Adam Abeshouse et al.
CELL (2015)
Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation
Jian An et al.
MOLECULAR CELL (2015)
SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression
Wenjian Gan et al.
MOLECULAR CELL (2015)
SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase
Hengrui Zhu et al.
CELL REPORTS (2015)
All-Trans Retinoic Acid Induces TGF-β2 in Intestinal Epithelial Cells via RhoA-and p38α MAPK-Mediated Activation of the Transcription Factor ATF2
Kopperuncholan Namachivayam et al.
PLOS ONE (2015)
Androgen Receptor Is the Key Transcriptional Mediator of the Tumor Suppressor SPOP in Prostate Cancer
Chuandong Geng et al.
CANCER RESEARCH (2014)
Destruction of DDIT3/CHOP Protein by Wild-Type SPOP but Not Prostate Cancer-Associated Mutants
Pingzhao Zhang et al.
HUMAN MUTATION (2014)
Destruction of Full-Length Androgen Receptor by Wild-Type SPOP, but Not Prostate-Cancer-Associated Mutants
Jian An et al.
CELL REPORTS (2014)
SPOP Mutations in Prostate Cancer across Demographically Diverse Patient Cohorts
Mirjam Blattner et al.
NEOPLASIA (2014)
The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications
Pascal Genschik et al.
EMBO JOURNAL (2013)
TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages
Lin Gao et al.
JOURNAL OF CELL SCIENCE (2013)
Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover
Chuandong Geng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
PKCε Promotes Oncogenic Functions of ATF2 in the Nucleus while Blocking Its Apoptotic Function at Mitochondria
Eric Lau et al.
CELL (2012)
ATF2-at the crossroad of nuclear and cytosolic functions
Eric Lau et al.
JOURNAL OF CELL SCIENCE (2012)
The mutational landscape of lethal castration-resistant prostate cancer
Catherine S. Grasso et al.
NATURE (2012)
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
Christopher E. Barbieri et al.
NATURE GENETICS (2012)
The genomic complexity of primary human prostate cancer
Michael F. Berger et al.
NATURE (2011)
A Role for ATF2 in Regulating MITF and Melanoma Development
Meera Shah et al.
PLOS GENETICS (2010)
OPINION Emerging roles of ATF2 and the dynamic AP1 network in cancer
Pablo Lopez-Bergami et al.
NATURE REVIEWS CANCER (2010)
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases
Min Zhuang et al.
MOLECULAR CELL (2009)
The role of ATF-2 in oncogenesis
Spiros A. Vlahopoulos et al.
BIOESSAYS (2008)
Suppressor role of activating transcription factor 2 (ATF2) in skin cancer
Anindita Bhoumik et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Tumor suppressor activity of glucocorticoid receptor in the prostate
A. Yemelyanov et al.
ONCOGENE (2007)
Reduced levels of ATF-2 predispose mice to mammary tumors
Toshio Maekawa et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
The p38 transduction pathway in prostatic neoplasia
M Ricote et al.
JOURNAL OF PATHOLOGY (2006)
Function and regulation of Cullin-RING ubiquitin ligases
MD Petroski et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases
R Geyer et al.
MOLECULAR CELL (2003)