4.5 Article

Porcupine inhibitors impair trabecular and cortical bone mass and strength in mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Medicine, General & Internal

Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis

Kenneth G. Saag et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, Research & Experimental

Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974

Jonathan D. Boone et al.

LABORATORY INVESTIGATION (2016)

Article Biochemistry & Molecular Biology

Wnt addiction of genetically defined cancers reversed by PORCN inhibition

B. Madan et al.

ONCOGENE (2016)

Article Medicine, General & Internal

Romosozumab Treatment in Postmenopausal Women with Osteoporosis

F. Cosman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Medicine, General & Internal

The WNT system: background and its role in bone

U. H. Lerner et al.

JOURNAL OF INTERNAL MEDICINE (2015)

Article Multidisciplinary Sciences

Notum deacylates Wnt proteins to suppress signalling activity

Satoshi Kakugawa et al.

NATURE (2015)

Editorial Material Multidisciplinary Sciences

CELL SIGNALLING Disarming Wnt

Roel Nusse

NATURE (2015)

Article Multidisciplinary Sciences

The bone-sparing effects of estrogen and WNT16 are independent of each other

Sofia Moverare-Skrtic et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

Sofia Moverare-Skrtic et al.

NATURE MEDICINE (2014)

Article Medicine, General & Internal

Romosozumab in Postmenopausal Women with Low Bone Mineral Density

Michael R. McClung et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Biochemistry & Molecular Biology

WNT signaling in bone homeostasis and disease: from human mutations to treatments

Roland Baron et al.

NATURE MEDICINE (2013)

Article Multidisciplinary Sciences

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

Jun Liu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Oncology

WNT signalling pathways as therapeutic targets in cancer

Jamie N. Anastas et al.

NATURE REVIEWS CANCER (2013)

Review Biochemistry & Molecular Biology

Wnt/β-Catenin Signaling and Disease

Hans Clevers et al.

Article Endocrinology & Metabolism

Update on Bone Anabolics in Osteoporosis Treatment: Rationale, Current Status, and Perspectives

Roland Baron et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

Review Oncology

Effects of Bone-Targeted Agents on Cancer Progression and Mortality

Robert Coleman et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2012)

Article Multidisciplinary Sciences

Wntless functions in mature osteoblasts to regulate bone mass

Zhendong Zhong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome

Jared J. Barrott et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Endocrinology & Metabolism

Wnt10b Deficiency Results in Age-Dependent Loss of Bone Mass and Progressive Reduction of Mesenchymal Progenitor Cells

Jennifer R. Stevens et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2010)

Article Cell Biology

Monounsaturated fatty acid modification of Wnt protein: Its role in Wnt secretion

Ritsuko Takada et al.

DEVELOPMENTAL CELL (2006)

Article Cell Biology

Wnt and calcium signaling:: β-Catenin-independent pathways

AD Kohn et al.

CELL CALCIUM (2005)

Review Medicine, General & Internal

Mechanisms of disease: Mechanisms of bone metastasis

GD Roodman

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Article Multidisciplinary Sciences

Wnt proteins are lipid-modified and can act as stem cell growth factors

K Willert et al.

NATURE (2003)