期刊
NATURE REVIEWS CANCER
卷 14, 期 8, 页码 517-534出版社
NATURE PORTFOLIO
DOI: 10.1038/nrc3774
关键词
-
类别
资金
- Terry Fox Research Institute, Vancouver, Canada
- Canadian Institute of Health Research
- Genome Canada
- Genome British Columbia
- Lymphoma Research Foundation US
B cell lymphomas are cancers that arise from cells that depend on numerous highly orchestrated interactions with immune and stromal cells in the course of normal development. Despite the recent focus on dissecting the genetic aberrations within cancer cells, it has been increasingly recognized that tumour cells retain a range of dependence on interactions with the non-malignant cells and stromal elements that constitute the tumour microenvironment. A fundamental understanding of these interactions gives insight into the pathogenesis of most B cell lymphomas and, moreover, identifies novel therapeutic opportunities for targeting oncogenic pathways, both now and in the future.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据