期刊
JOURNAL OF CLINICAL INVESTIGATION
卷 128, 期 2, 页码 545-555出版社
AMER SOC CLINICAL INVESTIGATION INC
DOI: 10.1172/JCI96702
关键词
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资金
- American Heart Association [16CSA28590003]
- NIH [R01DK100425, 5T32HL069772-15]
- US Department of Agriculture Agricultural Research Service [58-1950-4-003]
Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly harmful. Diets high in fructose can rapidly produce all of the key features of the metabolic syndrome. Here we review the biology of fructose metabolism as well as potential mechanisms by which excessive fructose consumption may contribute to cardiometabolic disease.
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