期刊
JOURNAL OF CHROMATOGRAPHY A
卷 1555, 期 -, 页码 37-44出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.chroma.2018.04.059
关键词
Porous organic framework; Solid-phase microextraction; Determination; Aromatic amines; Structure-activity relationship
资金
- National Natural Science Foundation of China [21771056, 21502044]
- Natural Science Foundation of Henan Province [162300410114, 162300410116]
- Science, Technology Development Program of Henan Province [172102310638]
- Program for Innovative Research Team of Henan Province [CXTD2017089]
A solid-phase microextraction (SPME) fiber coated with a two-dimensional porous organic framework (POF), JUC-Z2, was synthesized by a sol-gel process. The JUC-Z2-coated SPME fiber was combined with gas chromatography-mass spectrometry/mass spectrometry (GC-MS/MS), and a direct analysis method without any derivatization step was developed for the determination of two major harmful aromatic amines (1-naphthylamine, 1-NA; 2-naphthylamine, 2-NA) in the urine of amokers. The new method exhibited satisfactory linearity in the wide range of 0.05-100 pg L-1 with correlation coefficients (R) of 0.9999. The limits of detection are 0.010 and 0.012 ngL(-1). The relative standard deviations for repeated extraction (n = 6) with one fiber are less than 7.7%. The JUC-Z2-coated fiber demonstrates obviously superior extraction efficiencies for the two aromatic amines over the commercial fibers (CW/PEG, PA, PDMS/DVB, PDMS, CAR/PDMS, DVB/CAR PDMS). The structure-activity relationship was deeply investigated by the extraction comparison experiment with another similar POF material (PAF-48) and theoretical simulations. The extraction efficiencies of JUC-Z2 for 1-NA and 2-NA are 9.6 and 16.2 times higher than those of PAF-48, and JUC-Z2 has higher binding energies with the aromatic amines than PAF-48. The results indicate that the N atom on the JUZ-Z2 framework played a crucial role for adsorbing aromatic amines. Finally, the novel fiber has been successfully used to detect 1-NA and 2-NA in the urine of smokers. (C) 2018 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据