期刊
NEUROREHABILITATION AND NEURAL REPAIR
卷 28, 期 7, 页码 707-715出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1545968314521002
关键词
fcMRI; nerve injury; nerve repair; fMRI; early evaluation; peripheral nervous system; central nervous system; neuronal reorganization
资金
- N.I.H. [R01 EB000215]
Resting state functional connectivity magnetic resonance imaging studies in rat brain show brain reorganization caused by nerve injury and repair. In this study, distinguishable differences were found in healthy, nerve transection without repair (R-) and nerve transection with repair (R+) groups in the subacute stage (2 weeks after initial injury). Only forepaw on the healthy side was used to determine seed voxel regions in this study. Disturbance of neuronal network in the primary sensory region of cortex occurs within two hours after initial injury, and the network pattern was restored in R+ group in subacute stage, while the disturbed pattern remained in R- group. These are the central findings of the study. This technique provides a novel way of detecting and monitoring the effectiveness of peripheral nerve injury treatment in the early stage and potentially offers a tool for clinicians to avoid poor clinical outcomes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据