期刊
NATURE REVIEWS CANCER
卷 14, 期 10, 页码 683-691出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrc3798
关键词
-
类别
资金
- James S. McDonnell Foundation
- [R01CA138922]
- [R01CA173077]
Stem cell-based therapies are emerging as a promising strategy to tackle cancer. Multiple stem cell types have been shown to exhibit inherent tropism towards tumours. Moreover, when engineered to express therapeutic agents, these pathotropic delivery vehicles can effectively target sites of malignancy. This perspective considers the current status of stem cell-based treatments for cancer and provides a rationale for translating the most promising preclinical studies into the clinic.
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