期刊
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷 21, 期 8, 页码 826-831出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2018.1478814
关键词
Streptomyces; medermycin analog; cytotoxicity
资金
- National Natural Science Foundation of China [81402954]
- Zhejiang University Cross Researching Fund [JCZZ-2013021]
A new medermycin analog (1) was isolated from the marine-derived actinomycetes Streptomyces sp. ZS-A45. The structure elucidation of compound 1 was determined by the HRESIMS and extensive NMR analysis. And compound 1 exhibited significant cytotoxicity against PC3 cell lines with IC50 values of 0.81 +/- 0.42 mu m. [GRAPHICS] .
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