4.4 Article

Genomics innovation: transforming healthcare, business, and the global economy

期刊

GENOME
卷 58, 期 12, 页码 511-517

出版社

CANADIAN SCIENCE PUBLISHING
DOI: 10.1139/gen-2015-0121

关键词

genomics innovation; precision medicine; genomic medicine; genomic selection; agriculture

资金

  1. Consejo Nacional de Ciencia y Tecnologia (CONACYT) [224031, 249698]

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The genomics revolution has generated an unprecedented number of assets to propel innovation. Initial availability of genomics-based applications show a significant potential to contribute addressing global challenges, such as human health, food security, alternative sources of energies, and environmental sustainability. In the last years, most developed and emerging nations have established bioeconomy agendas where genomics plays a major role to meet their local needs. Genomic medicine is one of the most visible areas where genomics innovation is likely to contribute to a more individualized, predictive, and preventive medical practice. Examples in agriculture, dairy and beef, fishery, aquaculture, and forests industries include the effective selection of genetic variants associated to traits of economic value. Some, in addition to producing more and better foods, already represent an important increase in revenues to their respective industries. It is reasonable to predict that genomics applications will lead to a paradigm shift in our ability to ease significant health, economic, and social burdens. However, to successfully benefit from genomics innovations, it is imperative to address a number of hurdles related to generating robust scientific evidence, developing lower-cost sequencing technologies, effective bioin-formatics, as well as sensitive ethical, economical, environmental, legal, and social aspects associated with the development and use of genomics innovations.

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