期刊
JOURNAL OF ANTIBIOTICS
卷 71, 期 7, 页码 682-684出版社
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/s41429-018-0041-3
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资金
- Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)) from the Japan Agency for Medical Research and Development (AMED)
- 24th Botanical Research Grant of the New Technology Development Foundation
A new dipeptide, named tolyprolinol, was isolated from the static culture of a fungus, Tolypocladium sp. FKI-7981. The structure of tolyprolinol was elucidated as N-acetyl-L-phenylalanyl-L-prolinol. It showed moderate antimalarial activity but did not show cytotoxicity or any other antimicrobial property.
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