期刊
JOURNAL OF ALZHEIMERS DISEASE
卷 64, 期 1, 页码 91-102出版社
IOS PRESS
DOI: 10.3233/JAD-171061
关键词
Dementia; depression; risk factors; sexual minorities; subjective cognitive decline; subjective memory impairment
资金
- Human Resources Services Administration
- UCSF Center for Aging in Diverse Populations [P30AG015272]
- UCSF Older Americans Independence Center [P30AG044281]
- National Center for Advancing Translational Sciences of the National Institutes of Health [KL2TR001870]
- NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES [KL2TR001870] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [P30AG015272, P30AG044281] Funding Source: NIH RePORTER
Background: Little is known about subjective cognitive decline (SCD) in lesbian, gay, bisexual, and transgender (LGBT) older adults. Objectives: To examine SCD and its association with dementia risk factors, other physical and psychosocial health factors in LGBT older adults. Methods: A cross-sectional study of SCD was conducted with LGBT older adults, aged 50 and older (n = 210). SCD was categorized based on endorsement of memory problems and one other cognitive domain. Hierarchical logistic regression examined the associations between demographic factors, dementia risk factors, other health and psychosocial factors, and SCD. Results: Nearly 25% of LGBT older adults were classified as having SCD. LGBT older adults who were people of color (OR = 2.5; 95% CI = 1.1-7.8), depressed (OR = 2.9; 95% CI = 1.3-6.9), or reported having functional impairment (OR = 2.6; 95% CI = 1.1-6.5) were significantly more likely to be classified as having SCD (Nagelkerke pseudo R-2 = 0.27). Conclusion: Depression and functional impairment should be considered when screening LGBT older adults for cognitive impairment and dementia. Future research on the cognitive impairment and dementia risk in LGBT older adults is needed.
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