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May A. Beydoun et al.
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P. F. Giannopoulos et al.
MOLECULAR PSYCHIATRY (2014)
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Antonio Di Meco et al.
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Kausik Bishayee et al.
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Phillip F. Giannopoulos et al.
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5-Lipoxygenase pharmacological blockade decreases tau phosphorylation in vivo: involvement of the cyclin-dependent kinase-5
Jin Chu et al.
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Jin Chu et al.
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5-Lipoxygenase as an Endogenous Modulator of Amyloid beta Formation In Vivo
Jin Chu et al.
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Is hyperhomocysteinemia an Alzheimer's disease (AD) risk factor, an AD marker, or neither?
Jia-Min Zhuo et al.
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Olof Radmark et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
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J. -M. Zhuo et al.
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Johannes Levin et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2010)
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Henry W. Querfurth et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment
Niklas Mattsson et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)
S-Adenosylhomocysteine increases β-amyloid formation in BV-2 microglial cells by increased expressions of β-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters
Hung-Chi Lin et al.
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Yani Zou et al.
REJUVENATION RESEARCH (2009)
5-Lipoxygenase gene disruption reduces amyloid-β pathology in a mouse model of Alzheimer's disease
Omidreza Firuzi et al.
FASEB JOURNAL (2008)
A randomised double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer's disease
Peter J. Connelly et al.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2008)
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Paul S. Aisen et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)
Increased 5-Lipoxygenase Immunoreactivity in the Hippocampus of Patients With Alzheimer's Disease
Milos D. Ikonomovic et al.
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Cinzia M. Chinnici et al.
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Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses
Matthew G. Frank et al.
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Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid β peptide levels
Javier Pacheco-Quinto et al.
NEUROBIOLOGY OF DISEASE (2006)
Homocysteine and methylmalonic acid concentrations in cerebrospinal fluid:: relation with age and Alzheimer's disease
JM Serot et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2005)
Tau pathology in Alzheimer disease and other tauopathies
K Iqbal et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)
S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production
A Fuso et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2005)
The 5-lipoxygenase promoter is regulated by DNA methylation
J Uhl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Lipoxygenases and their involvement in programmed cell death
M Maccarrone et al.
CELL DEATH AND DIFFERENTIATION (2001)
Glucocorticoid receptors are required for up-regulation of neuronal 5-lipoxygenase (5LOX) expression by dexamethasone
T Uz et al.
FASEB JOURNAL (2001)
Metabolic regulation of brain Aβ by neprilysin
N Iwata et al.
SCIENCE (2001)
Neurodegenerative tauopathies
VMY Lee et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)