Effects of dietary administration of Chlorella on the immune status of gibel carp, Carassius auratus gibelio

In the present study the effects of dietary Chlorella on the immune status of gibel carp, Carassius auratus gibelio, were evaluated. A total of 540 healthy fish were divided into 6 groups, with one control group fed with Chlorella-free diet and five experimental groups fed diets supplemented with 0.4 to 2.0% Chlorella. The whole trial lasted 60 days. At the end of the trial, the weight gain and immune parameters of fish were analysed. Results showed that Chlorella could increase the levels of immunoglobulin M and D, interleukin-22 and chemokine (C-C motif) ligand 5 in some tissues, which indicated that dietary Chlorella can be involved in regulating adaptive and innate immunity.