期刊
GENOMICS DATA
卷 2, 期 -, 页码 230-236出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.gdata.2014.07.002
关键词
Adipocyte; ChIP-seq; Transcription factor
资金
- Fonds National de la Recherche Luxembourg [AFR]
- Fonds National de la Recherche Luxembourg [AM2c]
- Fonds National de la Recherche Luxembourg [C08/BM/01]
- University of Eastern Finland
- Fondation du Pelican de Mie et Pierre Hippert-Faber under the aegis of Fondation de Luxembourg
Transcription factors (TFs) represent key factors to establish a cellular phenotype. It is known that several TFs could play a role in disease, yet less is known so far how their targets overlap. We focused here on identifying the most highly induced TFs and their putative targets during human adipogenesis. Applying chromatin immunoprecipitation coupledwith deep sequencing (ChIP-Seq) in the human SGBS pre-adipocyte cell line, we identified genes with binding sites in their vicinity for the three TFs studied, PPAR., CEBPaandLXR. Here we describe the experimental design and quality controls in detail for the deep sequencing data and related results published by Galhardo et al. in Nucleic Acids Research 2014 [ 1] associated with the data uploaded to NCBI Gene Expression Omnibus (GSE41578). (C) 2014 The Authors. Published by Elsevier Inc.
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