期刊
INTERNATIONAL JOURNAL OF TOXICOLOGY
卷 37, 期 -, 页码 55S-66S出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1091581818776013
关键词
hydrolyzed wheat protein; hydrolyzed wheat gluten; safety; cosmetics
资金
- Personal Care Products Council
The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) reviewed the product use, formulation, and safety data on hydrolyzed wheat protein and hydrolyzed wheat gluten, which function as skin- and hair-conditioning agents. The Panel determined that data from clinical and laboratory studies were sufficient to demonstrate that these ingredients will not elicit type 1 immediate hypersensitivity reactions in sensitized individuals and will not induce sensitization when the polypeptide lengths of the hydrolysates do not exceed 30 amino acids. The Panel concluded that hydrolyzed wheat gluten and hydrolyzed wheat protein are safe for use in cosmetics when formulated to restrict peptides to an average molecular weight of 3,500 Da or less.
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