期刊
GENETIC TESTING AND MOLECULAR BIOMARKERS
卷 19, 期 3, 页码 124-127出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/gtmb.2014.0274
关键词
-
资金
- Project of Science and Technology Development Plan in Shandong Province [2012YD18009]
Background: Endothelial dysfunction is one of the most important early indicators of atherosclerosis in hypertension (HT) patients. Endocan has been reported to play a role in the pathophysiology of endothelial dysfunction. Objective: We sought to assess whether serum endocan levels are correlated with the presence and severity of coronary artery disease (CAD) in patients with HT. Methods: We measured endocan levels in 164 patients with HT and in 55 controls. The severity of CAD was assessed by the coronary atherosclerosis index scores. Results: Serum endocan levels were independently correlated with the presence and severity of CAD in HT patients. Conclusion: Endocan might function as a useful biomarker for monitoring the development and progression of CAD in HT patients.
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