期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 19, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/ijms19061569
关键词
mucinous epithelial ovarian cancer (mEOC); platinum-based therapy; KRAS
资金
- AIRC-Italian Association for Cancer Research [IG 19797]
Ovarian mucinous tumors represent a group of rare neoplasms with a still undefined cell of origin but with an apparent progression from benign to borderline to carcinoma. Even though these tumors are different from the other histological subtypes of epithelial ovarian neoplasms, they are still treated with a similar chemotherapeutic approach. Here, we review its pathogenesis, molecular alterations, (differential) diagnosis, clinical presentation and current treatment, and how recent molecular and biological information on this tumor might lead to better and more specific clinical management of patients with mucinous ovarian carcinoma.
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