期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 19, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/ijms19061618
关键词
vitamin D; non-phosphocalcic action; cellular functions; immune regulation; clinical effect
资金
- Sidra Medicine, Qatar
The classical function of Vitamin D, which involves mineral balance and skeletal maintenance, has been known for many years. With the discovery of vitamin D receptors in various tissues, several other biological functions of vitamin D are increasingly recognized and its role in many human diseases like cancer, diabetes, hypertension, cardiovascular, and autoimmune and dermatological diseases is being extensively explored. The non-classical function of vitamin D involves regulation of cellular proliferation, differentiation, apoptosis, and innate and adaptive immunity. In this review, we discuss and summarize the latest findings on the non-classical functions of vitamin D at the cellular/molecular level and its role in complex human diseases.
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