期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 109, 期 -, 页码 1068-1087出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2017.11.099
关键词
Gellan gum; Drug & gene delivery; Tissue engineering; Food industry; Oil recovery
Gellan gum (GG), a linear negatively charged exopolysaccharide,is biodegradable and non-toxic in nature. It produces hard and translucent gel in the presence of metallic ions which is stable at low pH. However, GG has poor mechanical strength, poor stability in physiological conditions, high gelling temperature and small temperature window. Therefore,it is blended with different polymers such as agar, chitosan, cellulose, sodium alginate, starch, pectin, polyanaline, pullulan, polyvinyl chloride, and xanthan gum. In this article, a comprehensive overview of combination of GG with natural and synthetic polymers/compounds and their applications in biomedical field involving drug delivery system, insulin delivery, wound healing and gene therapy, is presented. It also describes the utilization of GG based materials in food and petroleum industry. All the technical scientific issues have been addressed; highlighting the recent advancement. (C) 2017 Elsevier B.V. All rights reserved.
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