期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 108, 期 -, 页码 1074-1081出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2017.11.034
关键词
Fructooligosaccharides; Phagocytic activity; THP-1 cells; Smallanthus sonchifolius
资金
- Brazilian funding agency Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
- Brazilian funding agency Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
- Brazilian funding agency Fundacao Araucaria
Yacon (Smallanthus sonchifolius) originates from the Andean region and has spread across South America, Europe and Japan. In contrast with most roots, yacon stores its carbohydrates in fructooligosaccharides (FOS) and contains approximately 37% of FOS in its root dry matter. Aqueous extracts of yacon were characterized through TLC, methylation, NMR, and ESI-MS. FOS of yacon showed as linear fructooligosaccharides containing almost exclusively (2 -> 1)-linked beta-fructofuranosyl units, with terminal alpha-glucopyranosyl and beta-fructofuranosyl units. ESI-MS analyses indicated a wide degree of polymerization (DP) ranging from 2 to 10. The effect of the isolated FOS on non-specific immune activity by THP-1 cells was evaluated through phagocytic activity against heat-killed yeast (Saccharomices cerevisiae). The stimulant effect of yacon FOS was dose- and time-dependent, showing results more effective than branched FOS observed in previous studies. The results reinforce the use of linear yacon FOS as immunomodulators. (C) 2017 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据