期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 115, 期 -, 页码 1218-1224出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2018.04.129
关键词
Electrospinning; Mucilage; Nanofibers; Poly(vinyl alcohol); Tissue engineering
资金
- Ministry of Science, Technology and Telecommunications (MICITT)
- Innovation and Human Capital Program for Competitiveness (PINN)
- National Council for Scientific and Technological Research (CONICIT) of Costa Rica
Electrospun nanofibers (ESNFs) were prepared from mucilage isolated from chan and linaza beans and mozote stem commercially available in Costa Rica. Poly(vinyl alcohol) (PVA) was used as an aiding agent. Mucilage/PVA mixed solutions of different volume ratios (100:0, 80:20, 60:40, 40:60, 20:80 and 0:100) were prepared and adjusted to be similar in viscosity and electrical conductivity suitable for electrospinning. Morphology of the ESNFs was examined using scanning electron microscopy (SEM). Fourier transform infrared spectrometer (FTIR) and differential scanning calorimetry (DSC) studies were used to characterize chemical composition and thermal characteristics of the nanofibers (NFs). The ability of the NFs to support fibroblast cell proliferation was investigated in vitro using the optimized mucilage/PVA solutions. Results show plant mucilage-based ESNFs are well-suited for fibroblast cell growth, significantly better than ESNFs of PVA; and the mucilage of chan beans is better than those of mozote and linaza for supporting cell proliferation. (C) 2018 Elsevier B.V. All rights reserved.
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