期刊
IMMUNOTHERAPY
卷 10, 期 7, 页码 579-593出版社
FUTURE MEDICINE LTD
DOI: 10.2217/imt-2017-0138
关键词
allergen immunotherapy (AIT); allergic asthma; mechanisms; omalizumab; subcutaneous immunotherapy (SCIT); sublingual immunotherapy (SLIT)
类别
资金
- NIH [U19AI104209]
- Bezos Family Foundation
- FARE Center of Excellence
- Myra Reinhard Foundation
- Sean N. Parker Center for Allergy and Asthma Research at Stanford University
Although traditional pharmacological approaches improve outcomes in disease management for allergic asthma, these fail to modify the underlying immune responses. Allergen immunotherapy remains the only etiological therapy for the treatment of respiratory allergies for which clinical efficacy has been demonstrated through several well-controlled studies. In this review, we examine evidence from the past 5 years regarding the impact of allergen immunotherapy on allergic asthma to inform practitioners and stimulate further discussion and research.
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