期刊
HETEROCYCLES
卷 96, 期 2, 页码 324-333出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-17-13857
关键词
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Alkylative cyclization of 3-(2-isocyanophenyl)propenoic acid tent-butyl ester with Grignard reagents proceeds smoothly to form 2-alkyl-indole-3-acetic acid derivatives in moderate-to-good yields. Substituted 3-(2-isocyanophenyl)propenoic acid tert-butyl esters undergo a similar reaction when phenylmagnesium bromide is used to render 2-phenylindole-3-acetic acid derivatives in moderate-to-good yields.
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