期刊
GENE
卷 645, 期 -, 页码 157-162出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.gene.2017.12.036
关键词
Colorectal cancer; ceRNA; lncRNA; microRNA; RNA
资金
- Huzhou Public Welfare Technology Application Research Program [2016GYB14]
Colorectal cancer is one of the most common malignant tumours. Competitive endogenous RNA (ceRNA) networks have been hypothesized, in which various RNAs regulate each other's expression using microRNA response elements (MREs). Recent evidence has highlighted the crucial regulatory roles of ceRNA networks in colorectal cancer. In this review, we summarize the present research methods as well as the currently known ceRNA competitors and targets in colorectal cancer. In addition, we discuss the significance of ceRNA and shortcomings of current studies of colorectal cancer.
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