期刊
GENE
卷 640, 期 -, 页码 1-5出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.gene.2017.09.047
关键词
ABO blood group; Porcine; EAA; Genotyping; Deletion
资金
- Next-Generation Bio-Green21 Program of Rural Development Administration, Republic of Korea [PJ0111302017]
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science, ICT and future Planning [2015R1A5A1009701]
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education [2016R1A6A3A01007617]
- National Research Foundation of Korea [2016R1A6A3A01007617] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
The sequence information of the genomic form of the human ABO blood group orthologous gene (erythrocyte antigen A, EAA) is not complete in pigs. Therefore, we cloned and characterized the nucleotide sequence of EAA intron 7, which is critical to understand genetic difference between A and 0 blood groups in pigs, covering complete genomic sequence information of EAA excluding a similar to 560 bp unsequencible gap. We also analyzed genetic polymorphisms within EAA intron 7 and exon 8. We found difference in A0 blood group frequencies among pig breeds. In addition, we designed a new genomic DNA-based A0 blood group typing method and improved the accuracy and simplicity of the typing.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据