期刊
CRITICAL CARE
卷 19, 期 -, 页码 -出版社
BMC
DOI: 10.1186/s13054-015-0887-8
关键词
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资金
- Integra Lifesciences
- Neurologica
- Dana Foundation
- National Institutes of Health
- Swiss National Science Foundation [320030_138191]
- Novartis Foundation for Biomedical Research
- National Institutes of Health [U01 NS081041]
- National Institute for Health Research [NF-SI-0512-10090] Funding Source: researchfish
Neuroprotective strategies that limit secondary tissue loss and/or improve functional outcomes have been identified in multiple animal models of ischemic, hemorrhagic, traumatic and nontraumatic cerebral lesions. However, use of these potential interventions in human randomized controlled studies has generally given disappointing results. In this paper, we summarize the current status in terms of neuroprotective strategies, both in the immediate and later stages of acute brain injury in adults. We also review potential new strategies and highlight areas for future research.
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