期刊
FEMS MICROBIOLOGY REVIEWS
卷 39, 期 3, 页码 379-391出版社
OXFORD UNIV PRESS
DOI: 10.1093/femsre/fuv014
关键词
sRNAs; Hfq; evolution; mosaic pattern of selective pressure
类别
资金
- Intramural Research Programs of the National Library of Medicine
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
The increasing numbers of characterized base-pairing small RNAs (sRNAs) and the identification of these regulators in a broad range of bacteria are allowing comparisons between species and explorations of sRNA evolution. In this review, we describe some examples of trans-encoded base-pairing sRNAs that are species-specific and others that are more broadly distributed. We also describe examples of sRNA orthologs where different features are conserved. These examples provide the background for a discussion of mechanisms of sRNA evolution and selective pressures on the sRNAs and their mRNA target(s).
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