期刊
FOOD RESEARCH INTERNATIONAL
卷 103, 期 -, 页码 280-288出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.foodres.2017.10.058
关键词
Inonotus obliquus polysaccharides; Gastrointestinal digestion; Physiochemical property; Antioxidant activity; alpha-amylase and alpha-glucosidase inhibitory activities
资金
- National Natural Science Foundation of China [NSFC 31371879]
- National High Technology Research and Development Program (863 Program) of China [SS2013AA100207]
This study was aimed to investigate the impacts of gastrointestinal digestion in vitro on the physicochemical properties and the biological activities of polysaccharides from Inonolus obliquus (UIOPS-1). Results showed that the monosaccharides composition, structure and conformation of polysaccharides were remarkably altered, and the molecular weight (Mw) of UIOPS-1 was steadily decreased from 105.02 kDa to 88.97 kDa and 36.74 kDa after simulated digestion. The reducing ends were increased and the free monosaccharides including D-glucose, D-galactose and D-xylose were released suggested that the degradation of UIOPS-1 was caused by disrupting the aggregates and glycosidic bonds. The antioxidant activities of UIOPS-1 were significantly increased after gastric digestion (P < 0.05), however, they were decreased after intestinal digestion. The D-amylase and alpha-glucosidase inhibitory activities of UIOPS-1 were significantly increased after digestion indicating a good control of postprandial hyperglycemia (P < 0.001). The results indicated that UIOPS-1 still exhibited antioxidant and anti hyperglycemic potential after gastrointestinal digestion, which could be considered as a promising candidate for functional foods.
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