期刊
ANNALS OF CLINICAL AND LABORATORY SCIENCE
卷 45, 期 2, 页码 193-198出版社
ASSOC CLINICAL SCIENTISTS
关键词
Heavy/light chain; plasma cell myeloma; monitoring
We report three cases of plasma cell myeloma with obscure and discordant data for a monoclonal component. In this study, the results of serum heavy/light chain (sHLC) were retrospectively compared with those of conventional methods during disease monitoring. All three patients achieved a complete response and experienced a relapse during follow-up, and the sHLC ratio allowed early prediction of disease relapse and correlated well with other electrophoretic methods compared with the free light chain ratio. Therefore, we suggest that the sHLC assay may be useful as a complementary tool; it has a good correlation with conventional methods and sensitivity in assessing disease status and treatment response in patients with plasma cell myeloma.
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