期刊
FOOD CHEMISTRY
卷 264, 期 -, 页码 108-117出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2018.05.006
关键词
Antioxidant peptides from Pinctada fucata; Primary structure; Spatial conformation; Structure-activity
资金
- China Agriculture Research System, China [CARS-47]
- National Natural Science Foundation of Guangdong, China [2016A030313144]
- Special Project of Marine fishery technology and industrial development in Guangdong province [Z2015008]
Antioxidant peptides from Pinctada fucata are ubiquitous in nature and can be utilized as ingredients in cosmetics or functional foods to positively regulate oxidative species in the human body against oxidation. Here, mutated peptides and a homologous series of peptides were designed and prepared, based on the original peptide sequence of an antioxidant peptide from Pinctada fucata meat (PFMAP), to better understand the structural relationships, including primary structure, spatial conformation and activity. The results showed that the antioxidant activity factors in order of importance were spatial conformation, amino acid sequence, amino acid position, amino acid composition, peptide chain length and degree of side-chain amino acid glycosylation. Moreover, this protocol had incomparable advantages in purity, speed and cost of preparing polypeptides, relative to enzymatic hydrolysis or chemosynthesis methods. This study also supplies test data information and a theoretical basis for the higher-value application of polypeptides from marine sources.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据