期刊
JBJS REVIEWS
卷 3, 期 5, 页码 -出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.2106/JBJS.RVW.N.00064
关键词
-
类别
Significance reporting in clinical trials can be misleading because of factors such as overpowering, choosing clinically insignificant outcomes, and inappropriate subgroup analysis. Clinical significance generally refers to a change that is important to a patient, although clinical significance can also be reported through the viewpoints of health-care providers or health-care policy-makers. Clinical significance can be measured in a number of ways, including minimally important difference, responder analysis, patient acceptable symptom state, and substantial clinical benefit. Orthopaedic cost-effectiveness and value analyses should include a measure of clinical significance to ensure relevance to patients.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据