期刊
FERTILITY AND STERILITY
卷 109, 期 6, 页码 1079-+出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2018.02.124
关键词
Deep endometriosis; digestive function; fertility; pain; postoperative complications; pregnancy
资金
- G4 Group (The University Hospitals of Rouen, Lille, Amiens, and Caen)
- ROUENEN-DOMETRIOSE Association
Objective: To report postoperative outcomes after surgery for deep endometriosis without involvement of the digestive or urinary tracts. Design: Retrospective study using data prospectively recorded in the North-West Inter Regional Female Cohort for Patients with Endometriosis (CIRENDO) database. Setting: University tertiary referral center. Patient(s): One hundred thirty consecutive patients whose follow-up ranged from 1 to 6 years. Intervention(s): Laparoscopic excision of deep endometriosis nodules. Main Outcome Measure(s): Postoperative complications were recorded in the CIRENDO database and medical charts. Postoperative digestive function was assessed using standardized gastrointestinal questionnaires: the Gastrointestinal Quality of Life Index and the Knowles-Eccersley-Scott Symptom Questionnaire. Result(s): Deep endometriosis nodules involved uterosacral ligaments, rectovaginal space, and vagina and spared the bowel, the bladder, and the ureters. Nodule size was <1 cm, 1-3 cm, and >3 cm in diameter in 20.8%, 64.6%, and 14.6% of cases, respectively. Clavien-Dindo 1, 2, and 3b complications occurred in 0.8%, 4.6%, and 5.4% of cases, respectively. Among Clavien-Dindo 3b complications, most involved pelvic hematoma. Gastrointestinal scores revealed significant improvement in digestive function or defecation pain at 1 and 3 years after surgery. The pregnancy rate was, respectively, 43.3% and 56.7% at 1 and 3 years postoperatively, among which 66.7% and 64.7% were spontaneous conceptions. Conclusion(s): Our data suggest that surgery for deep endometriosis without involvement of the digestive or urinary tracts provides a low rate of postoperative complications and satisfactory fertility outcomes. (C) 2018 by American Society for Reproductive Medicine.
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