相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。TRPM2 dependence of ROS-induced NLRP3 activation in Alzheimer's disease
Malihe Aminzadeh et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
Resveratrol loaded solid lipid nanoparticles attenuate mitochondrial oxidative stress in vascular dementia by activating Nrf2/HO-1 pathway
Aarti Yadav et al.
NEUROCHEMISTRY INTERNATIONAL (2018)
Mitochondrial dysfunction in Parkinsonian mesenchymal stem cells impairs differentiation
Plamena R. Angelova et al.
REDOX BIOLOGY (2018)
Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases
Nathan A. Berger et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation
Marta Delgado-Camprubi et al.
CELL DEATH AND DIFFERENTIATION (2017)
The discovery of Alzheimer-causing mutations in the APP gene and the formulation of the amyloid cascade hypothesis
John Hardy
FEBS JOURNAL (2017)
Deuterium-reinforced polyunsaturated fatty acids improve cognition in a mouse model of sporadic Alzheimer's disease
Ahmed Elharram et al.
FEBS JOURNAL (2017)
Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin
Bin Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
Zhiwei Dong et al.
MOLECULAR CELL (2017)
iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease
Charles Arber et al.
PLOS ONE (2017)
KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients
Luisa Quinti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration
Noemi Esteras et al.
REDOX BIOLOGY (2017)
Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates
Fernando Bartolome et al.
SCIENTIFIC REPORTS (2017)
Interaction of misfolded proteins and mitochondria in neurodegenerative disorders
Andrey Y. Abramov et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2017)
Mitochondrial Permeability Transition Pore as a Suitable Target for Neuroprotective Agents Against Alzheimer's Disease
Elena F. Shevtsova et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2017)
Alpha-synuclein and beta-amyloid different targets, same players: calcium, free radicals and mitochondria in the mechanism of neurodegeneration
Plamena R. Angelova et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease
Emma Deas et al.
ANTIOXIDANTS & REDOX SIGNALING (2016)
Mitochondrial dysfunction in neocortex and hippocampus of olfactory bulbectomized mice, a model of Alzheimer's disease
A. V. Avetisyan et al.
BIOCHEMISTRY-MOSCOW (2016)
Oxidation of NADH and ROS production by respiratory complex I
Andrei D. Vinogradov et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2016)
Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration
Daniel I. Orellana et al.
EMBO MOLECULAR MEDICINE (2016)
Mitochondrial ROS regulation of proliferating cells
Lauren Diebold et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
Functional role of mitochondrial reactive oxygen species in physiology
Plamena R. Angelova et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase
Marthe H. R. Ludtmann et al.
JOURNAL OF NEUROSCIENCE (2016)
'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich's ataxia'
R. Abeti et al.
CELL DEATH & DISEASE (2016)
Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts
Elisa Onesto et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2016)
SIRT2-and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models
Luisa Quinti et al.
CELL CHEMICAL BIOLOGY (2016)
The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics
Albena T. Dinkova-Kostova et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2015)
Nrf2 regulates ROS production by mitochondria and NADPH oxidase
Stjepana Kovac et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2015)
Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction
Kerri J. Kinghorn et al.
BRAIN (2015)
Lipid peroxidation is essential for α-synuclein-induced cell death
Plamena R. Angelova et al.
JOURNAL OF NEUROCHEMISTRY (2015)
Cu(II) enhances the effect of Alzheimer's amyloid-β peptide on microglial activation
Fengxiang Yu et al.
JOURNAL OF NEUROINFLAMMATION (2015)
Functional Oxygen Sensitivity of Astrocytes
Plamena R. Angelova et al.
JOURNAL OF NEUROSCIENCE (2015)
Targeting lipid peroxidation and mitochondrial imbalance in Friedreich's ataxia
Rosella Abeti et al.
PHARMACOLOGICAL RESEARCH (2015)
Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons
A. K. Reeve et al.
CELL DEATH & DISEASE (2015)
PKA Phosphorylation of NCLX Reverses Mitochondria! Calcium Overload and Depolarization, Promoting Survival of PINK1-Deficient Dopaminergic Neurons
Marko Kostic et al.
CELL REPORTS (2015)
Rare Individual Amyloid-β Oligomers Act on Astrocytes to Initiate Neuronal Damage
Priyanka Narayan et al.
BIOCHEMISTRY (2014)
The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease
Li Fang Ng et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Soluble, Prefibrillar α-Synuclein Oligomers Promote Complex I-dependent, Ca2+-induced Mitochondrial Dysfunction
Eric S. Luth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Lipid peroxidation is essential for phospholipase C activity and the inositol-trisphosphate-related Ca2+ signal
Ana-Marija Domijan et al.
JOURNAL OF CELL SCIENCE (2014)
PINK1 deficiency in β-cells increases basal insulin secretion and improves glucose tolerance in mice
Emma Deas et al.
OPEN BIOLOGY (2014)
UCP2 overexpression worsens mitochondrial dysfunction and accelerates disease progression in a mouse model of amyotrophic lateral sclerosis
Pablo M. Peixoto et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2013)
Properties of native brain α-synuclein
Jacqueline Burre et al.
NATURE (2013)
Amyotrophic Lateral Sclerosis: New Insights into Underlying Molecular Mechanisms and Opportunities for Therapeutic Intervention
Mauro Cozzolino et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model
Dario Brunetti et al.
HUMAN MOLECULAR GENETICS (2012)
Cerebral Hypoperfusion and Cognitive Impairment: The Pathogenic Role of Vascular Oxidative Stress
Hui Liu et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2012)
Mechanism of Oxidative Stress in Neurodegeneration
Sonia Gandhi et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Dopamine Induced Neurodegeneration in a PINK1 Model of Parkinson's Disease
Sonia Gandhi et al.
PLOS ONE (2012)
Mitochondrial dysfunction in ALS
Mauro Cozzolino et al.
PROGRESS IN NEUROBIOLOGY (2012)
β-amyloid activates PARP causing astrocytic metabolic failure and neuronal death
Rosella Abeti et al.
BRAIN (2011)
Amyloid β-Induced Impairments in Hippocampal Synaptic Plasticity Are Rescued by Decreasing Mitochondrial Superoxide
Tao Ma et al.
JOURNAL OF NEUROSCIENCE (2011)
The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease
Meagan J. McManus et al.
JOURNAL OF NEUROSCIENCE (2011)
Bioenergetic Consequences of PINK1 Mutations in Parkinson Disease
Andrey Yurevich Abramov et al.
PLOS ONE (2011)
Signaling Functions of Reactive Oxygen Species
Henry Jay Forman et al.
BIOCHEMISTRY (2010)
Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations
Andrey Y. Abramov et al.
BRAIN (2010)
Dopamine Induces Ca2+ Signaling in Astrocytes through Reactive Oxygen Species Generated by Monoamine Oxidase
Annika Vaarmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
Jaime N. Guzman et al.
NATURE (2010)
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
Heng Du et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Oxidative Stress Involvement in α-Synuclein Oligomerization in Parkinson's Disease Cybrids
A. Raquel Esteves et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Parkinson's disease and nursing home placement: the economic impact of the need for care
C. Vossius et al.
EUROPEAN JOURNAL OF NEUROLOGY (2009)
DJ-1 Changes in G93A-SOD1 Transgenic Mice: Implications for Oxidative Stress in ALS
Nirit Lev et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2009)
PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-induced Cell Death
Sonia Gandhi et al.
MOLECULAR CELL (2009)
Emerging pathways in genetic Parkinson's disease: Potential role of ceramide metabolism in Lewy body disease
Jose Bras et al.
FEBS JOURNAL (2008)
Optical Reporters for the Conformation of α-Synuclein Reveal a Specific Interaction with Mitochondria
Ken Nakamura et al.
JOURNAL OF NEUROSCIENCE (2008)
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
Heng Du et al.
NATURE MEDICINE (2008)
Mitochondrial Respiratory Dysfunction in Familiar Parkinsonism Associated with PINK1 Mutation
Claudia Piccoli et al.
NEUROCHEMICAL RESEARCH (2008)
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6
Hans-Hermann Hoepken et al.
NEUROBIOLOGY OF DISEASE (2007)
Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation
Andrey Y. Abramov et al.
JOURNAL OF NEUROSCIENCE (2007)
PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron
Neil V. Morgan et al.
NATURE GENETICS (2006)
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
A Bender et al.
NATURE GENETICS (2006)
The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides
AY Abramov et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2005)
Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain
N Zhang et al.
STROKE (2005)
Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress
HM Li et al.
FREE RADICAL RESEARCH (2005)
Mitochondrial Aβ:: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
C Caspersen et al.
FASEB JOURNAL (2005)
The alpha-ketoglutarate-dehydrogenase complex - A mediator between mitochondria and oxidative stress in neurodegeneration
GE Gibson et al.
MOLECULAR NEUROBIOLOGY (2005)
Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease
ZB Andrews et al.
JOURNAL OF NEUROSCIENCE (2005)
β-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase
AY Abramov et al.
JOURNAL OF NEUROSCIENCE (2004)
Mitochondrial α-ketoglutarate dehydrogenase complex generates reactive oxygen species
AA Starkov et al.
JOURNAL OF NEUROSCIENCE (2004)
Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-β peptides via p75NTR/PLAIDD
Y Hashimoto et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Calcium signals induced by amylold β peptide and their consequences in neurons and astrocytes in culture
AY Abramov et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2004)
Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants
RA Gonzalez-Polo et al.
CELL BIOLOGY INTERNATIONAL (2004)
Oxidatively modified proteins in aging and disease
MF Beal
FREE RADICAL BIOLOGY AND MEDICINE (2002)
beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities
CS Casley et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Δψm-dependent and -independent production of reactive oxygen species by rat brain mitochondria
TV Votyakova et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients
N Shibata et al.
BRAIN RESEARCH (2001)
Transgenic mouse model for familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation
N Shibata
NEUROPATHOLOGY (2001)