期刊
JOURNAL OF PEDIATRIC GENETICS
卷 4, 期 2, 页码 71-83出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0035-1556739
关键词
obesity; body mass index; pregnancy; major congenital malformations
类别
Obesity is a growing global health epidemic. It is estimated that more than 20% of pregnancies are complicated by obesity. Prepregnancy obesity has been associated with birth defects such as neural tube defects, macrosomia, fetal death, and long-term effects such as asthma on the offspring. We provide a summary of the most recent studies and meta-analyses on obesity and birth outcome. Possible mechanisms of actions are explored and recommendations for further research are highlighted.
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