期刊
ANTIOXIDANTS
卷 4, 期 2, 页码 293-303出版社
MDPI
DOI: 10.3390/antiox4020293
关键词
radiation induced skin toxicity; calendula; complementary and alternative medicine; radiodermatitis; radiation induced dermatitis; cancer
Calendula is a topical agent derived from a plant of the marigold family Calendula Officinalis. Containing numerous polyphenolic antioxidants, calendula has been studied in both the laboratory and clinical setting for the use in treating and preventing radiation induced skin toxicity. Despite strong evidence in the laboratory supporting calendula's mechanism of action in preventing radiation induced skin toxicity, clinical studies have demonstrated mixed results. In light of the controversy surrounding the efficacy of calendula in treating and preventing radiodermatitis, the topic warrants further discussion.
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